HPLC Determination of Trimellitic anhydride on Newcrom BH

HPLC-Applikation • Datum: 2021/02/08
HPLC Determination of Trimellitic anhydride on Newcrom BH Chromatogramm

High Performance Liquid Chromatography (HPLC) Method for Analysis of Trimellitic anhydride .

Trimellitic anhydride is a trifunctional, highly reactive aromatic anhydride with the chemical formula C9H4O5 . It is used as a curing agent for epoxy and other resins; in vinyl plasticizers, paints, coatings, dyes, pigments and a wide variety of other manufactured products.

Trimellitic anhydride can be retained in HPLC with a Newcrom BH mixed-mode column using a mobile phase of acetonitrile (ACN) and water and Sulfuric Acid (H2SO4) buffer allowing the use of a UV detector at 210 nm.

Methodenparameter

ColumnNewcrom BH, 3.2 x 100 mm, 5 µm, 100 Å, dual ended
Mobile PhaseMeCN/H2O – 5/95%
BufferH2SO4 – 0.2%
Flow Rate0.5 mL/min
Detection210 nm