HPLC Determination of DMAPS on Primesep S Column

HPLC-Applikation • Datum: 2020/04/01
HPLC Determination of  DMAPS on Primesep S Column Chromatogramm

High Performance Liquid Chromatography (HPLC) Method for Analysis of 3-[Dimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azaniumyl]propane-1-sulfonate (DMAPS) .

3-[Dimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azaniumyl]propane-1-sulfonate (DMAPS) , also known as DMAPS, is a hygroscopic zwitterionic monomer with the chemical formula C11H21NO5S . It is typically used for the synthesis of polysulfobetaines, which are useful in many biomedical applications.

3-[Dimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azaniumyl]propane-1-sulfonate (DMAPS) can be retained and analyzed using the Primesep S stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN). Detection is performed using CAD.

Methodenparameter

ColumnPrimesep S2, 4.6 x 150 mm, 5 µm, 100 Å, dual ended
Mobile PhaseMeCN/H2O – 70/30%
BufferNo
Flow Rate1.0 mL/min
DetectionCAD, MS- compatible mobile phase