HPLC Determination of Carbocisteine on Primesep 100 Column

HPLC-Applikation • Datum: 2019/07/31
HPLC Determination of Carbocisteine on Primesep 100 Column Chromatogramm

High Performance Liquid Chromatography (HPLC) Method for Analysis of Carbocisteine , S-(Carboxymethyl)-L-cysteine .

Carbocisteine, or carbocysteine, is a drug designed to clear the mucus from the upper and lower airways. It’s primarily available in tablet form. It can be retained on a Primesep 100 Column in about 5 minutes. Primesep 100 is a reverse-phase (RP) mixed-mode column with embedded acidic ion-pairing groups.

Methodenparameter

ColumnPrimesep 100
Mobile PhaseMeCN/H2O – 10/90%
BufferH2SO4 – 0.05%
Flow Rate1.0 mL/min
DetectionUV, 200 nm