Alltesta HPLC Method for Analysis of Losartan on Newcrom R1 Column
Separation type: Liquid Chromatography Reversed-phase
Losartan is a medication that belongs to a class of drugs known as angiotensin II receptor blockers (ARBs).
Losartan can be retained, and analyzed on a reversed-phase Newcrom R1 column with a mobile phase consisting of water, Acetonitrile (MeCN), and sulfuric acid. This analytical method can be detected with high resolution and peak symmetry at a wavelength of 200 nm using UV detection
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Methodenparameter
| Column | Newcrom R1, 3.2 x 100 mm, 5 µm, 100 Å, dual ended |
|---|---|
| Mobile Phase | MeCN/H2O – 30/70%, |
| Buffer | H2SO4 – 0.1% |
| Flow Rate | 0.5 mL/min |
| Detection | UV 275 nm |