HPLC Separation of Sodium, Potassium Ions and Tetramethylammonium Chloride on Newcrom AH Column
High Performance Liquid Chromatography (HPLC) Method for Analysis of Tetramethylammonium , Sodium , Potassium .
Tetramethylammonium chloride is a quaternary ammonium salt used widely as a reagent in industrial applications. It can be separated from sodium and potassium chlorides on a mixed-mode Newcrom AH column with a simple isocratic MS-compatible mobile phase of water, acetonitrile (ACN) and ammonium formate (AmFm) buffer.
Methodenparameter
| Column | Newcrom AH, 4.6 x 150 mm, 5 µm, 100 Å, dual ended |
|---|---|
| Mobile Phase | MeCN/H2O – 50/50% |
| Buffer | AmFm pH 3.0- 10 mM |
| Flow Rate | 1.0 mL/min |
| Detection | CAD (Corona) MS- compatible mobile phase |