HPLC Separation of Sodium, Chloride, Bromide, and Iodine

HPLC-Applikation • Datum: 2010/11/21
HPLC Separation of Sodium, Chloride, Bromide, and Iodine Chromatogramm

Halide ions are usually analyzed by ion-chromatography with a conductivity detector. Mixed-mode chromatography in combination with ELSD is offering a valuable alternative to ion-chromatography with conductivity detection. Chloride, bromide and iodide were separated on a Primesep SB mixed-mode anion-exchange column. Mobile phase is compatible with ELSD and LC/MS.

Methodenparameter

ColumnPrimesep SB, 4.6×50 mm, 5 µm, 100 Å
Mobile PhaseMeCN/H2O
BufferAmFm
Flow Rate1.0 mL/min
DetectionELSD