HPLC Determination of Sodium Dodecyl Sulfate on Primesep B4 Column
High Performance Liquid Chromatography (HPLC) Method for Analysis of Sodium dodecyl sulfate .
Sodium dodecyl sulfate, or sodium lauryl sulfate, is a surfactant used in cleaning and hygienic products. It has a twelve carbon hydrophobic tail attached to a polar sulfate. Dodecyl sulfate can be retained on Primesep B4 column in under 5 minutes with an MS-compatible mobile phase. Primesep B4 is a short carbon chain reverse-phase (RP) mixed-mode column with embedded basic ion-pairing groups.
Methodenparameter
| Column | Primesep B4 |
|---|---|
| Mobile Phase | MeCN/H2O – 60/40% |
| Buffer | AmFm pH 3.0 – 30 mM |
| Flow Rate | 1.0 mL/min |
| Detection | CAD (Corona) MS- compatible mobile phase |