HPLC Method for Analysis of m-Xylylenediamine (MXDA) on BIST™ B+ Column

Separation type: Bridge Ion Separation Technology, or BIST™

BIST Ionic Modifier Preparation

High Performance Liquid Chromatography (HPLC) Method for Analysis of m- Xylylenediamine (MXDA)

HPLC Method for Analysis of m-Xylylenediamine on a BIST™ B Column. m-Xylylenediamine (MXDA) is a popular curing agent used on epoxy resins. Using SIELC’s newly introduced BIST™ method, MXDA, which protonates in water, can be retained on a positively-charged anion-exchange BIST™ B column. There are two keys to this retention method: 1) a multi-charged, negative buffer, such as Sulfuric acid (H2SO4), which acts as a bridge, linking the positively-charged MXDA analytes to the positively-charged column surface and 2) a mobile phase consisting mostly of organic solvent (such as MeCN) to minimize the formation of a solvation layer around the charged analytes. Using this new and unique analysis method, MXDA can be retained and UV detected at 210 nm.