Applikationen / HPLC Analysis of Valproic Acid using Mixed-Mode Chromatography

HPLC Analysis of Valproic Acid using Mixed-Mode Chromatography

HPLC-Applikation • Datum: 2010/05/06
HPLC Analysis of Valproic Acid using Mixed-Mode Chromatography Chromatogramm

Separation type: Liquid Chromatography Mixed-mode

Valproic acid is a chemical compound used as a convulsant and mood-stabilizing drug. Valproic acid is hydrophobic compound containing carboxylic acid. It is retained on a Primesep B2 column by combination of reversed-phase and anion-exchange mechanism.

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Methodenparameter

ColumnPrimesep B2, 4.6×50 mm, 5 µm, 100 Å
Mobile PhaseMeCN
BufferAmmonum Acetate pH 4.0 – 10 mM
Flow Rate1.0 mL/min
DetectionELSD

Direktzugriff

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