HPLC Method for Analysis of Phthalic acid on Primesep B Column

Chromatogram

Description

· Separation type: Liquid Chromatography Mixed-mode SIELC Technologies · HPLC Method for Analysis of Phthalic Acid on Primesep B Column

Phthalic acid is an aromatic dicarboxylic acid with the chemical formula C₆H₄(CO₂H)₂. It consists of a benzene ring with two carboxylic acid groups (-COOH) attached to adjacent carbon atoms (in the ortho position). It is mainly produced by the oxidation of naphthalene or o-xylene.

Uses Phthalic acid is primarily used as a precursor to other chemicals, including:

Phthalic anhydride: Used in the production of plasticizers for PVC (polyvinyl chloride). Alkyd resins: Important in the manufacture of paints and coatings. Dyes and pigments: Phthalic acid derivatives are often used in the production of dyes.

Phthalic Acid can be retained, separated and analyzed using a Primesep B mixed-mode stationary phase column. The analysis employs a gradient method with a simple mobile phase comprising water, acetonitrile (MeCN), and phosphoric acid as a buffer. This method allows for detection using UV 200 nm.

You can find detailed UV spectra of Phthalic Acid and information about its various lambda maxima by visiting the following link .

Method Parameters

HPLC Column Used