Analysis of Codeine and Related Impurities in Drug Composition

https://sielc.com/Application-Analysis-of-Codeine-and-Related-Impurities-in-Drug-Composition
⬇ PDF Download

Chromatogram

Method Parameters

Mobile PhaseMeCN/H2O – 35/65%
BufferTEAPh Ph 3.5 – 15 Mm
Flow Rate1.0 ml/min
DetectionUV, 210 nm
Class of CompoundsDrug, Preservatives,  Base, Hydrophobic, Ionizable
Analyzing CompoundsCodeine, Methyl Paraben, Propyl Paraben

HPLC Column Used

Primesep C, 4.6×150 mm, 5 µm, 100A