HPLC Method for Analysis of (R)-(+)-1-(1-Naphthyl)-ethylamine on Primesep 200 Column
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Description
· HPLC Method for Analysis of (R)-(+)-1-(1-Naphthyl)-ethylamine in on Primesep 200 Column
(R)-(+)-1-(1-Naphthyl)-ethylamine is a chiral aromatic amine with the molecular formula C 12 H 13 N . It is used primarily as a core chiral building block as well as an intermediate in chemical synthesis. You can find detailed UV spectra of [ compounds ] and information about its various lambda maxima by visiting the following link .
(R)-(+)-1-(1-Naphthyl)-ethylamine can be retained and analyzed using the Primesep 200 stationary phase column. The analysis utilizes an isocratic method with a mobile phase consisting of acetonitrile, water, and Ammonium Formate. Detection is performed using LC MS and UV.
Method Parameters
| Mobile Phase | MeCN/H2O – 50/50% |
|---|---|
| Buffer | Ammonium Formate pH 3.0 – 10 mM |
| Flow Rate | 0.5 ml/min |
| Detection | ESI-SIM: [M+H]+m/z 1189172, UV 278 nm |
| LOD* | 10 ppb |
| Class of Compounds | Drug |
| Analyzing Compounds | (R)-(+)-1-(1-Naphthyl)-ethylamine |
HPLC Column Used
Primesep 200, 3.2 x 150 mm, 3 µm, 100 A, dual ended