HPLC Method for Analysis of Zidesamtinib on Chromni Column

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Chromatogram

Description

· High Performance Liquid Chromatography (HPLC) Method for Analysis of Zidesamtinib .

Zidesamtinib is an anti-cancer medication with the chemical formula C 22 H 22 FN 7 O . It is primarily used to treat non-small cell lung cancer and works as a kinase inhibitor.

Zidesamtinib can be retained and analyzed using the Chromni stationary phase column. The analysis utilizes a gradient method with a simple mobile phase consisting of water and acetonitrile (MeCN) and ethanol. Detection is performed using UV.

Method Parameters

Mobile PhaseMeCN/H2O
BufferAmAc pH 7.0 – 20 mM
Flow Rate1.0 ml/min
DetectionUV 260 nm
Class of CompoundsDrugs
Analyzing CompoundsZidesamtinib

HPLC Column Used

Chromni, 4.6 x 150 mm, 3 µm, 100 A, dual ended
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