HPLC Method for Analysis of Vilazodone in Pharmaceutical Formulation on Primesep 100 Column
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Description
· High Performance Liquid Chromatography (HPLC) Method for Analysis of Vilazodone .
Vilazodone is a serotonin modulator with the chemical formula C 26 H 27 N 5 O 2 . It is primarily used to treat major depressive disorder. You can find detailed UV spectra of Vilazodone and information about its various lambda maxima by visiting the following link.
Vilazodone can be retained and analyzed using the Primesep 100 stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN). Detection is performed using UV.
Method Parameters
| Mobile Phase | MeCN/H2O – 50/50 |
|---|---|
| Buffer | H2SO4 – 0.2% |
| Flow Rate | 1.0 ml/min |
| Detection | UV 240 nm |
| Limit Of Detection* | 80 ppb |
| Class of Compounds | Drug |
| Analyzing Compounds | Vilazodone |
HPLC Column Used
Primesep 100, 4.6 x 150 mm, 5 µm, 100 A, dual ended