HPLC Method for Analysis of Venlafaxine on Chromni Column

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Chromatogram

Description

· High Performance Liquid Chromatography (HPLC) Method for Analysis of Venlafaxine

Venlafaxine serotonin-norepinephrine reuptake inhibitor (SNRI) with the molecular formula C 17 H 27 NO 2 .

Properties: Appearance: Variety of tablets and capsules as determined by the distributor · Molecular weight: ~277.402 g/mol · Solubility: Soluble in water. · Uses: Medication for treating Major Depressive Disorder

Venlafaxine can be retained and analyzed using the Chromni stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water, acetonitrile (MeCN). Detection is performed using UV.

Method Parameters

Mobile PhaseMeCN – 15%
BufferPhosphoric Acid
Flow Rate1.0 ml/min
DetectionUV 275 nm
Class of Compoundstertiary amino
Analyzing CompoundsVenlafaxine

HPLC Column Used

Chromni, 4.6 x 150 mm, 3 µm, 100 A, dual ended
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