HPLC Method for Analysis of Trimellitic Acid on Newcrom BH Column on Alltesta™

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Chromatogram

Description

· High Performance Liquid Chromatography (HPLC) Method for Analysis of Trimellitic Acid

Trimellitic Acid is an isomer of benzenetricarboxylic acid with the chemical formula C 9 H 6 O 6 . It is primarily used as carboxylate ligand in the synthesis of a wide range of metal-organic frameworks (MOFs).

Trimellitic Acid can be retained and analyzed using the Newcrom BH stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with sulfuric acid as a buffer. Detection is performed using UV.

Method Parameters

Mobile PhaseMeCN – 10%
BufferSulfuric Acid
Flow Rate1.0 mL/min
DetectionUV 275 nm
Class of CompoundsAcid
Analyzing CompoundsTrimellitic Acid

HPLC Column Used

Newcrom BH, 4.6 x 150 mm, 3 µm, 100 A, dual ended