
· High Performance Liquid Chromatography (HPLC) Method for Analysis of Trimellitic Acid
Trimellitic Acid is an isomer of benzenetricarboxylic acid with the chemical formula C 9 H 6 O 6 . It is primarily used as carboxylate ligand in the synthesis of a wide range of metal-organic frameworks (MOFs).
Trimellitic Acid can be retained and analyzed using the Newcrom BH stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with sulfuric acid as a buffer. Detection is performed using UV.
| Mobile Phase | MeCN – 10% |
|---|---|
| Buffer | Sulfuric Acid |
| Flow Rate | 1.0 mL/min |
| Detection | UV 275 nm |
| Class of Compounds | Acid |
| Analyzing Compounds | Trimellitic Acid |