HPLC Method for Analysis of Ropinirole in Pharmaceutical Formulation on Primesep 100 Column
https://sielc.com/hplc-method-for-analysis-of-ropinirole-2Chromatogram
Description
· High Performance Liquid Chromatography (HPLC) Method for Analysis of Ropinirole .
Ropinirole is an drug with the chemical formula C 16 H 24 N 2 O . It is primarily used to treat Parkinson’s disease and restless leg syndrome. It works as a D 2 , D 3 , and D 4 dopamine receptor agonist. You can find detailed UV spectra of Ropinirole and information about its various lambda maxima by visiting the following link.
Ropinirole can be retained and analyzed using the Primesep 100 stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN). Detection is performed using UV.
Method Parameters
| Mobile Phase | MeCN/H2O – 60/40 |
|---|---|
| Buffer | H2SO4 – 0.2% |
| Flow Rate | 1.0 ml/min |
| Detection | UV 195 nm |
| Limit Of Detection* | 3 ppb |
| Class of Compounds | Drug |
| Analyzing Compounds | Ropinirole |
HPLC Column Used
Primesep 100, 4.6 x 150 mm, 5 µm, 100 A, dual ended