HPLC Method For Analysis of B-Cyclodextrin and Hydroxypropyl B-Cyclodextrin on Primesep S2 Column

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Chromatogram

Description

High Performance Liquid Chromatography (HPLC) Method for Analysis of B-Cyclodextrin and Hydroxypropyl B-Cyclodextrin.

Beta-cyclodextrin has the chemical formula C 42 H 70 O 35 . It is used in a large variety of industries primarily as a complexing agent.  It’s most notable uses are in medicine as sustained release drugs carrier and to improve stability in drugs.

Hydroxypropyl B-Cyclodextrin is a Oligosaccharide drug with the chemical formula C 63 H 112 O 42 . It is used as a complexing agent.

Method Parameters

Mobile PhaseMeCN- 70%
BufferNo
Flow Rate1.0 ml/min
DetectionELSD
Class of CompoundsSugar
Analyzing Compoundsbeta-CYCLODEXTRIN,Hydroxypropyl B-Cyclodextrin

HPLC Column Used

Primesep S2, 4.6 x 150 mm, 5 µm, 100 A, dual ended