HPLC Method for Analysis of 1-Bromopropane on Newcrom R1 Column

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Chromatogram

Description

· High Performance Liquid Chromatography (HPLC) Method for Analysis of 1-Bromopropane

1-Bromopropane , or n-propylbromide , is a popular industrial solvent with the chemical formula CH 3 CH 2 CH 2 Br . It has a wide variety of applications, the list of which is growing as chlorofluorocarbons are being phased out. Applications include aerosolized adhesives, asphalt production, aviation maintenance, and in synthetic fiber production. It is highly neurotoxic to humans. You can find detailed UV spectra of 1-Bromopropane and information about its various lambda maxima by visiting the following link.

1-Bromopropane can be retained and analyzed on a Newcrom R1 reverse-phase column using a simple isocratic analytical method with a mobile phase consisting of just Acetonitrile (MeCN) and water (with no ionic modifier). This analysis method can be UV detected at 210 nm with high resolution and peak symmetry.

Method Parameters

Mobile PhaseMeCN – 55%
BufferNone
Flow Rate1.0 ml/min
DetectionUV 210 nm
Class of CompoundsAlkyl bromides
Analyzing Compounds1-Bromopropane

HPLC Column Used

Newcrom R1, 4.6 x 150 mm, 3 µm, 100 A, dual ended