HPLC Determination of DMAPS on Primesep S Column
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Description
High Performance Liquid Chromatography (HPLC) Method for Analysis of 3-[Dimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azaniumyl]propane-1-sulfonate (DMAPS) .
3-[Dimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azaniumyl]propane-1-sulfonate (DMAPS) , also known as DMAPS, is a hygroscopic zwitterionic monomer with the chemical formula C 11 H 21 NO 5 S . It is typically used for the synthesis of polysulfobetaines, which are useful in many biomedical applications.
3-[Dimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azaniumyl]propane-1-sulfonate (DMAPS) can be retained and analyzed using the Primesep S stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN). Detection is performed using CAD.
Method Parameters
| Mobile Phase | MeCN/H2O – 70/30% |
|---|---|
| Buffer | No |
| Flow Rate | 1.0 ml/min |
| Detection | CAD, MS- compatible mobile phase |
| Class of Compounds | Hydrophobic, Polar, Zwitterion |
| Analyzing Compounds | 3-[Dimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azaniumyl]propane-1-sulfonate (DMAPS) |