HPLC Determination of Carbocisteine on Primesep 100 Column
https://sielc.com/hplc-determination-of-carbocisteineChromatogram
Carbocisteine
Description
High Performance Liquid Chromatography (HPLC) Method for Analysis of Carbocisteine , S-(Carboxymethyl)-L-cysteine .
Carbocisteine, or carbocysteine, is a drug designed to clear the mucus from the upper and lower airways. It’s primarily available in tablet form. It can be retained on a Primesep 100 Column in about 5 minutes. Primesep 100 is a reverse-phase (RP) mixed-mode column with embedded acidic ion-pairing groups.
Method Parameters
| Mobile Phase | MeCN/H2O – 10/90% |
|---|---|
| Buffer | H2SO4 – 0.05 % |
| Flow Rate | 1.0 ml/min |
| Detection | UV, 200 nm |
| Class of Compounds | Acid, Hydrophilic, Ionizable, Carboxylic acid, Drug, Carbocyclic, Amino acid |
| Analyzing Compounds | Carbocisteine,S-(Carboxymethyl)-L-cysteine |
HPLC Column Used
Primesep 100