HPLC Chiral Separation of N-benzyl-alpha-methylbenzylamine Enantiomers on Cyralis CM Column

Chromatogram

Description

High Performance Liquid Chromatography (HPLC) Method for Analysis of (S)-(-)-N-Benzyl-1-phenylethylamine .

(S)-(-)-N-Benzyl-1-phenylethylamine is a organic compound with the chemical formula C 15 H 17 N .

This application describes a normal-phase chiral HPLC method for the separation of (S)-(-)-N-Benzyl-1-phenylethylamine enantiomers using SIELC’s Cyralis CM chiral column. Cyralis CM is a cellulose-based chiral stationary phase (CSP) designed for enantiomeric separations, optical purity testing, chiral impurity analysis, and stereoisomer characterization in pharmaceutical, chemical, agrochemical, and fine chemical applications. For best results, the sample should be prepared fresh for analysis.

(S)-(-)-N-Benzyl-1-phenylethylamine can be retained and analyzed using the Cyralis CM stationary phase column. The analysis utilizes an isocratic method with a mobile phase consisting of hexane, IPA, and DEA. Detection is performed using UV.

Method Parameters

HPLC Column Used