HPLC Chiral Separation of 2-Phenylpropylamine Enantiomers on Cyralis AL Column

Chromatogram

Description

· High Performance Liquid Chromatography (HPLC) Method for Analysis of 2-Phenylpropylamine .

2-Phenylpropylamine is an organic compound with the chemical formula C 9 H 13 N . Not much is known about the substance, but it shares properties with amphetamine. It is said to have antihypotensive activity. It is associated with a case of cerebral hemorrhage in Sweden.

You can find detailed UV spectra of 2-Phenylpropylamine and information about its various lambda maxima by visiting the following link.

This application describes a normal-phase chiral HPLC method for the separation of [compound] enantiomers using SIELC’s Cyralis AL chiral column. Cyralis AL is an amylose-based chiral stationary phase (CSP) designed for enantiomeric separations, optical purity testing, chiral impurity analysis, and stereoisomer characterization in pharmaceutical, chemical, agrochemical, and fine chemical applications.

2-Phenylpropylamine can be retained and analyzed using the Cyralis AL stationary phase column. The analysis utilizes an isocratic method with a mobile phase consisting of Hexane, IPA, and 1-butylamine. Detection is performed using UV.

Method Parameters

HPLC Column Used