HPLC Chiral Separation of (2-Methoxy-1-pyridin-2-ylethyl)methylamine Enantiomers on Cyralis AM Column

https://sielc.com/hplc-chiral-method-for-analysis-of-2-methoxy-1-pyridin-2-ylethylmethylamine
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Chromatogram

Description

High Performance Liquid Chromatography (HPLC) Method for Analysis of (2-Methoxy-1-pyridin-2-ylethyl)methylamine .

(2-Methoxy-1-pyridin-2-ylethyl)methylamine is an organic compound with the chemical formula C 9 H 14 N2 O . You can find detailed UV spectra of (2-Methoxy-1-pyridin-2-ylethyl)methylamine and information about its various lambda maxima by visiting the following link.

This application describes a normal-phase chiral HPLC method for the separation of (2-Methoxy-1-pyridin-2-ylethyl)methylamine enantiomers using SIELC’s Cyralis AM chiral column. Cyralis AM is an amylose-based chiral stationary phase (CSP) designed for enantiomeric separations, optical purity testing, chiral impurity analysis, and stereoisomer characterization in pharmaceutical, chemical, agrochemical, and fine chemical applications.

(2-Methoxy-1-pyridin-2-ylethyl)methylamine can be retained and analyzed using the Cyralis AM stationary phase column. The analysis utilizes an isocratic method with a mobile phase consisting of Hexane, Ethanol, and DEA. Detection is performed using UV.

Method Parameters

Mobile PhaseHexane/Ethanol/DEA
Flow Rate1.0 mL/min
DetectionUV 220 nm
Resolution2.13
Class of CompoundsOragnic
Analyzing Compounds(2-Methoxy-1-pyridin-2-ylethyl)methylamine

HPLC Column Used

Cyralis AM, 4.6 x 100 mm, 5 µm, 100 A, normal phase