HPLC Chiral Separation of 1-phenyl-2-propanol Enantiomers on Cyralis CM Column

Chromatogram

Description

· High Performance Liquid Chromatography (HPLC) Method for Analysis of 1-Phenyl-2-propanol .

1-phenyl-2-propanol is a chiral secondary alcohol with the chemical formula C 9 H 12 O . It is primarily used in chemical research as well as as a fragrance. It has a sweet scent with a honey-like undertone. You can find detailed UV spectra of 1-Phenyl-2-propanol and information about its various lambda maxima by visiting the following link.

This application describes a normal-phase chiral HPLC method for the separation of 1-Phenyl-2-propanol enantiomers using SIELC’s Cyralis CM chiral column. Cyralis CM is a cellulose-based chiral stationary phase (CSP) designed for enantiomeric separations, optical purity testing, chiral impurity analysis, and stereoisomer characterization in pharmaceutical, chemical, agrochemical, and fine chemical applications. For best results, the sample should be prepared fresh for analysis.

1-Phenyl-2-propanol can be retained and analyzed using the Cyralis CM stationary phase column. The analysis utilizes an isocratic method with a mobile phase consisting of Hexane and Ethanol. Detection is performed using UV.

Method Parameters

HPLC Column Used