HPLC Method for Separation of 1-Benzylpiperidine-4-carbaldehyde on Primesep 100 Column
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Description
High Performance Liquid Chromatography (HPLC) Method for Analysis of 1-Benzylpiperidine-4-carbaldehyde
1-Benzylpiperidine-4-carbaldehyde is an organic chemical with the chemical formula C 13 H 17 NO . It is primarily used in pharmaceutical and medicinal chemistry research as a building block and as a key intermediate in the synthesis of Donepezil. Its reactive aldehyde group and piperidine ring make it useful for synthesizing biologically active compounds. You can find detailed UV spectra of 1-Benzylpiperidine-4-carbaldehyde and information about its various lambda maxima by visiting the following link.
1-Benzylpiperidine-4-carbaldehyde can be retained and analyzed using the Primesep 100 stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of acetonitrile (MeCN). Detection is performed using UV.
Method Parameters
| Mobile Phase | MeCN/H2O – 70/30% |
|---|---|
| Buffer | Sulfuric Acid – 0.1% |
| Flow Rate | 1.0 ml/min |
| Detection | UV 208 nm |
| Limit of Detection* | 34 ppb |
| Class of Compounds | Organic |
| Analyzing Compounds | 1-Benzylpiperidine-4-carbaldehyde |