HPLC Separation of Methylphosphonic Acid and Related Products

https://sielc.com/Application-HPLC-Separation-of-Methylphosphonic-Acid-and-Related-Products
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Chromatogram

Description

Alkylphosphonic acids are decomposition byproducts of chemical warfare agents. Analysis of phosphonic acid in water is regulated by Environmental Protection Agency (EPA). All phosphonic acids are polar acidic compounds. Analysis for retention and separation of methylphosphonic, ethylphosphonic, ethyl methylphosphonic and isopropyl methylphosphonic acids was developed using Primesep SB reversed-phase anion-exchange column. Method is compatible with LC/MS and can be used for quantitation of phosphonic acid in water.

Method Parameters

Mobile PhaseMeCN
BufferAmAc
Flow Rate1.0 ml/min
DetectionELSD
Class of CompoundsAcid,  Hydrophilic, Ionizable
Analyzing CompoundsMethylphosphonic, Ethylphosphonic, Ethyl methylphosphonic, Isopropyl methylphosphonic acids

HPLC Column Used

Primesep SB, 4.6×150 mm, 5 µm, 100A
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Data source & disclaimer: The HPLC application data, chromatograms and method parameters on this page are sourced from SIELC Technologies and are provided for informational and educational purposes only. All trademarks, column names and product designations remain the property of their respective owners.
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