HPLC Method for Analysis of Trimipramine

https://sielc.com/HPLC-Method-Analysis-Trimipramine
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Chromatogram

Chr_1063

Chr_1063

Description

Trimipramine is a tricyclic antidepressant with antihistamine and sedative properties. It acts by decreasing the reuptake of norepinephrine and serotonin (5-HT), which is why it is used as treatment of major depressive disorder. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Trimipramine. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

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