HPLC Method for Analysis of Etodolac

https://sielc.com/HPLC-Method-Analysis-Etodolac
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Chromatogram

14

14

Description

Etodolac is a pyrenecarboxylic acid and non-steroidal anti-inflammatory drug (NSAID). It reduces pain, swelling, and joint stiffness by blocking the production of certain natural substances that cause inflammation. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Meclizine. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Method Parameters

Mobile PhaseMeCN – 40%
BufferH3PO4 – 0.1%,
Flow Rate0.5 ml/min
DetectionUV, 270 nm
Class of CompoundsDrug,  Acid, Hydrophilic, Ionizable, Supplements
Analyzing CompoundsEtodolac

HPLC Column Used

Primesep 200, 3.2×100 mm, 5 µm, 100A