HPLC Analysis of Valproic Acid using Mixed-Mode Chromatography

https://sielc.com/Application-HPLC-Analysis-of-Valproic-Acid-Using-Mixed-Mode-Chromatography
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Chromatogram

Description

Valproic acid is a chemical compound used as a convulsant and mood-stabilizing drug. Valproic acid is hydrophobic compound containing carboxylic acid. It is retained on a Primesep B2 column by combination of reversed-phase and anion-exchange mechanism.

Method Parameters

Mobile PhaseMeCN
BufferAmmonum Acetate pH 4.0 – 10 mM
Flow Rate1.0 ml/min
DetectionELSD
Class of CompoundsAcid
Analyzing CompoundsValproic Acid

HPLC Column Used

Primesep B2, 4.6×50 mm, 5 µm, 100A
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Data source & disclaimer: The HPLC application data, chromatograms and method parameters on this page are sourced from SIELC Technologies and are provided for informational and educational purposes only. All trademarks, column names and product designations remain the property of their respective owners.
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