HPLC Analysis of Paracetamol
https://sielc.com/Application-HPLC-Analysis-of-ParacetamolChromatogram
Description
Paracetamol (also known as acetaminophen) is a mild analgesic commonly used for relief from headaches and used in many cold and flu medicines. Legacy L1 was used to retain Paracetamol by reverse phase mechanism. Legacy L1 uses embedded C18 groups on porous silica and is useful for many USP HPLC applications. comparisons to Phenomenex columns are available by request.
Method Parameters
| Mobile Phase | MeOH – 15% |
|---|---|
| Buffer | AmAc pH 4.0- 42 mM |
| Flow Rate | 1.0 ml/min |
| Detection | UV, 257 nm |
| Class of Compounds | Drug, Hydrophilic, Ionizable |
| Analyzing Compounds | Paracetamol |
HPLC Column Used
Legacy L1, 4.6×250 mm, 5 µm, 100A