HPLC Method for Analysis of Propranolol on Primesep 100 Column

HPLC-Applikation • Datum: 2025/07/14
HPLC Method for Analysis of Propranolol on Primesep 100 Column Chromatogramm

High Performance Liquid Chromatography (HPLC) Method for Analysis of Propranolol

Propranolol is an organic compound with the molecular formula C16H21NO2 .

Properties: Appearance: Typically a stable, odorless, white to off-white crystalline powder.

Molecular weight: ~259.34 g/mol

Solubility: Soluble in water and ethanol.

Uses: A non-selective beta-blocker. Used to treat a variety of conditions, both cardiovascular and non-cardiovascular.

Methodenparameter

ColumnPrimesep 100, 4.6 x 150 mm, 5 µm, 100 Å, dual ended
Mobile PhaseMeCN – 70%
BufferH2SO4 – 0.1%
Flow Rate1.0 mL/min
DetectionUV 270 nm
Limit of Detection14 ppb