HPLC Method for Analysis of Etodolac
Etodolac is a pyrenecarboxylic acid and non-steroidal anti-inflammatory drug (NSAID). It reduces pain, swelling, and joint stiffness by blocking the production of certain natural substances that cause inflammation. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Meclizine. The method is UV compatible and can be used as a general approach for analyzing similar compounds.
Methodenparameter
| Column | Primesep 200, 3.2×100 mm, 5 µm, 100 Å |
|---|---|
| Mobile Phase | MeCN – 40% |
| Buffer | H3PO4 – 0.1%, |
| Flow Rate | 0.5 mL/min |
| Detection | UV, 270 nm |