HPLC Method For Analysis of Cyclodextrins on Primesep S2
High Performance Liquid Chromatography (HPLC) Method for Analysis of B-Cyclodextrin, G-Cyclodextrin and A-Cyclodextrin
Cyclodextrins are hexasaccharides that are natural starch-conversion products. Industrially, they are manufactured by enzymatic degradation of vegetable raw materials.
Alpha-cyclodextrin has the chemical formula C36H60O30 . It is said to lower blood pressure, cholesterol, and glucose levels. It is primarily used as a dietary supplement for fiber.
Beta-cyclodextrin has the chemical formula C42H70O35 . It is used in a large variety of industries primarily as a complexing agent. It’s most notable uses are in medicine as sustained release drugs carrier and to improve stability in drugs.
Gamma-cyclodextrin has the chemical formula C48H80O40 . It is used as a complexing agent due to having the largest cavity size between the natural cyclodextrin. It has use across a variety of industries from food, to medicine, to textiles, and cosmetics.
Methodenparameter
| Column | Primesep S2, 4.6 x 150 mm, 5 µm, 100 Å, dual ended |
|---|---|
| Mobile Phase | MeCN- 70% |
| Buffer | AmFm pH 3.0- 20 mm |
| Flow Rate | 1.0 mL/min |
| Detection | ELSD |