HPLC Method for Analysis of Cerium(III) Nitrate on Newcrom AH Column

Separation type: Liquid Chromatography Mixed-mode

Cerium(III) is a specific oxidation state of the element cerium, which is a lanthanide and a rare-earth metal.

Cerium(III) compounds are often used in a variety of applications. For example, cerium(III) chloride (CeCl3) is a common starting material for the preparation of other cerium-containing compounds and is often used as a reducing agent in organic chemistry. Cerium(III) oxide (Ce2O3), also known as cerous oxide, is used in ceramics and to polish glass.

Cerium(III) nitrate is often used in the laboratory as a cerium(III) source because it is relatively stable and easy to handle. It can be used in a variety of reactions, such as the preparation of other cerium compounds or as a catalyst or co-catalyst in organic reactions.

Cerium(III) Nitrate can be retained and analyzed on a mixed-mode Newcrom AH, 4.6 x 100 mm, 5 µm, 100 Å, dual ended column with a mobile phase consisting of water, Acetonitrile (MeCN), and Ammonium Formate. This analysis method can be detected with an Evaporative Light Scattering Detector (ELSD) or any other evaporative detection method (CAD, ESI-MS).

LOD was determined for this combination of instrument, method, and analyte, and it can vary from one laboratory to another even when the same general type of analysis is being performed.